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Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice

Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants o...

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Bibliografiske detaljer
Principais autores: James C. Zimring, Ariel M. Hay, Monika Dzieciatkowska, Daniel Stephenson, Zachary B. Haiman, Steven Kleinman, Philip J. Norris, Michael P. Busch, Nareg Roubinian, Elisa Fermo, Paola Bianchi, Gregory R. Keele, Grier P. Page, Angelo D'Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-01-01
Serier:HemaSphere
Online adgang:https://doi.org/10.1002/hem3.70288
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