Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions

BACKGROUND Patients with sickle cell disease (SCD) frequently receive RBC units stored near the end of their permissible storage duration. We aimed to determine whether RBC storage duration influences recipient hematological, metabolic, and clinical chemistry parameters.METHODS In a randomized, pros...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Matthew S. Karafin, Abby L. Grier, Ross M. Fasano, Anton Ilich, David Wichlan, Ada Chang, Sonjile M. James, Hailly E. Butler, Oleg Kolupaev, Melissa C. Caughey, Daniel J. Stephenson, Julie A. Reisz, Nigel S. Key, Joshua J. Field, Jane A. Little, Steven L. Spitalnik, Angelo D’Alessandro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2025-09-01
Schriftenreihe:	The Journal of Clinical Investigation
Schlagworte:	Clinical Research Hematology
Online-Zugang:	https://doi.org/10.1172/JCI192920
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!