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Multiomic approach and Mendelian randomization analysis identify causal associations between blood biomarkers and subcortical brain structure volumes

Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) have identified numerous common variants associated with brain structure. In this study, we integrate...

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Detalhes bibliográficos
Principais autores: Pritesh R Jain, Madison Yates, Carlos Rubin de Celis, Petros Drineas, Neda Jahanshad, Paul Thompson, Peristera Paschou
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-12-01
coleção:NeuroImage
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1053811923006171
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