Multiomic approach and Mendelian randomization analysis identify causal associations between blood biomarkers and subcortical brain structure volumes

Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) have identified numerous common variants associated with brain structure. In this study, we integrate...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Pritesh R Jain, Madison Yates, Carlos Rubin de Celis, Petros Drineas, Neda Jahanshad, Paul Thompson, Peristera Paschou
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-12-01
Цуврал:	NeuroImage
Нөхцлүүд:	Subcortical brain volume Proteome Metabolites Mendelian randomization Neurological disorders
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1053811923006171
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!