Multiomic approach and Mendelian randomization analysis identify causal associations between blood biomarkers and subcortical brain structure volumes

Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) have identified numerous common variants associated with brain structure. In this study, we integrate...

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Detalles Bibliográficos

Principais autores:	Pritesh R Jain, Madison Yates, Carlos Rubin de Celis, Petros Drineas, Neda Jahanshad, Paul Thompson, Peristera Paschou
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2023-12-01
Series:	NeuroImage
Assuntos:	Subcortical brain volume Proteome Metabolites Mendelian randomization Neurological disorders
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S1053811923006171
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