Activation of Platelet NLRP3 Inflammasome in Crohn’s Disease

Patients with Crohn’s disease (CD) are inclined to have platelet hyperactivity and an increased risk of intestinal micro-thrombosis. However, the mechanisms underlying platelet hyperactivity in CD are not well understood. We investigated the assembly of platelet NLRP3 inflammasome in patients with a...

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Hlavní autoři:	Ge Zhang, He Chen, Yifan Guo, Wei Zhang, Qiuyu Jiang, Si Zhang, Liping Han, She Chen, Ruyi Xue
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-06-01
Edice:	Frontiers in Pharmacology
Témata:	NLRP3 inflammasome Crohn’s disease platelet hyperactivity ROS interleukin-1β
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.705325/full
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