NLRP3 inflammasome activation contributes to the cognitive decline after cardiac surgery

BackgroundPerioperative neurocognitive disorders (PND) are a common complication of cardiac surgery in elderly patients. The etiopathogenesis of PND is not clear. Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, a macromolecular protein complex, regulates inflammation by indu...

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Autors principals:	Gang Ma, Ping Sun, Yi Chen, Xin Jiang, Caixia Zhang, Baofu Qu, Xiangkun Meng
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-11-01
Col·lecció:	Frontiers in Surgery
Matèries:	NLRP3 inflammasome perioperative neurocognitive disorders (PND) inflammation interleukin - 1β interleukin
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fsurg.2022.992769/full
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