Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

Summary: Hhex encodes a homeobox transcriptional regulator important for embryonic development and hematopoiesis. Hhex is highly expressed in NK cells, and its germline deletion results in significant defects in lymphoid development, including NK cells. To determine if Hhex is intrinsically required...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Wilford Goh, Sebastian Scheer, Jacob T. Jackson, Soroor Hediyeh-Zadeh, Rebecca B. Delconte, Iona S. Schuster, Christopher E. Andoniou, Jai Rautela, Mariapia A. Degli-Esposti, Melissa J. Davis, Matthew P. McCormack, Stephen L. Nutt, Nicholas D. Huntington
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2020-10-01
Ráidu:	Cell Reports
Fáttát:	NK cells proliferation survival apoptosis BIM transcriptional regulation
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S2211124720312742
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!