Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Daniela S. Arroyo, Emilia A. Gaviglio, Javier M. Peralta Ramos, Claudio Bussi, Maria P. Avalos, Liliana M. Cancela, Pablo Iribarren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-04-01
coleção:	Frontiers in Immunology
Assuntos:	myeloid cells phosphatidyl-inositol-3 kinase inhibitors autophagy peptidoglycan TLR2 inflammation
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00770/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!