Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Hlavní autoři:	Daniela S. Arroyo, Emilia A. Gaviglio, Javier M. Peralta Ramos, Claudio Bussi, Maria P. Avalos, Liliana M. Cancela, Pablo Iribarren
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-04-01
Edice:	Frontiers in Immunology
Témata:	myeloid cells phosphatidyl-inositol-3 kinase inhibitors autophagy peptidoglycan TLR2 inflammation
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00770/full
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