Phosphatidyl-Inositol-3 Kinase Inhibitors Regulate Peptidoglycan-Induced Myeloid Leukocyte Recruitment, Inflammation, and Neurotoxicity in Mouse Brain

Acute brain injury leads to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral myeloid cells (MC), which contribute to the inflammatory response involved in neuronal damage. We previously reported that TLR2 stimulation by peptidoglycan (PGN) from...

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Ngā kaituhi matua:	Daniela S. Arroyo, Emilia A. Gaviglio, Javier M. Peralta Ramos, Claudio Bussi, Maria P. Avalos, Liliana M. Cancela, Pablo Iribarren
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2018-04-01
Rangatū:	Frontiers in Immunology
Ngā marau:	myeloid cells phosphatidyl-inositol-3 kinase inhibitors autophagy peptidoglycan TLR2 inflammation
Urunga tuihono:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00770/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!