Defects of mitochondria-lysosomes communication induce secretion of mitochondria-derived vesicles and drive chemoresistance in ovarian cancer cells

Abstract Background Among the mechanisms of mitochondrial quality control (MQC), generation of mitochondria-derived vesicles (MDVs) is a process to avoid complete failure of mitochondria determining lysosomal degradation of mitochondrial damaged proteins. In this context, RAB7, a late endocytic smal...

Descripción completa

Detalles Bibliográficos

Autores principales:	Sinforosa Gagliardi, Marco Mitruccio, Riccardo Di Corato, Roberta Romano, Alessandra Aloisi, Rosaria Rinaldi, Pietro Alifano, Flora Guerra, Cecilia Bucci
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-03-01
Colección:	Cell Communication and Signaling
Materias:	RAB7 Mitochondria-derived vesicles Extracellular vesicles Cisplatin chemoresistance Ovarian cancer
Acceso en línea:	https://doi.org/10.1186/s12964-024-01507-y
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!