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Rab32 and Rab38 maintain bone homeostasis by regulating intracellular traffic in osteoclasts

Osteoclasts play a crucial role in bone homeostasis by forming resorption pits on bone surfaces, resulting in bone resorption. The osteoclast expression of Rab38 protein is highly induced during differentiation from macrophages. Here we generated mice with double knockout (DKO) of Rab38 and its para...

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Autori principali: Kanako Tokuda, Shiou-Ling Lu, Zidi Zhang, Yumiko Kato, Siyu Chen, Kazuya Noda, Katsutoshi Hirose, Yu Usami, Narikazu Uzawa, Shinya Murakami, Satoru Toyosawa, Mitsunori Fukuda, Ge-Hong Sun-Wada, Yoh Wada, Takeshi Noda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japan Society for Cell Biology 2023-10-01
Serie:Cell Structure and Function
Soggetti:
rab32
rab38
osteoclast
lysosome-related organelle
secretory lysosome
Accesso online:https://www.jstage.jst.go.jp/article/csf/48/2/48_23061/_html/-char/en
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