Dynamics and quantitative contribution of the aminoglycoside 6′-N-acetyltransferase type Ib to amikacin resistance

ABSTRACTAminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health. Among the multitude of modifying enzymes that confer resistance to aminog...

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Detalhes bibliográficos

Principais autores:	Ophélie d’Udekem d’Acoz, Fong Hue, Tianyi Ye, Louise Wang, Maxime Leroux, Lucila Rajngewerc, Tung Tran, Kimberly Phan, Maria S. Ramirez, Walter Reisner, Marcelo E. Tolmasky, Rodrigo Reyes-Lamothe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2024-03-01
Colecção:	mSphere
Assuntos:	amikacin antibiotic resistance fluorescence AAC(6′)-Ib Escherichia coli CRISPRi
Acesso em linha:	https://journals.asm.org/doi/10.1128/msphere.00789-23
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