p53 and Zinc: A Malleable Relationship
A large percentage of transcription factors require zinc to bind DNA. In this review, we discuss what makes p53 unique among zinc-dependent transcription factors. The conformation of p53 is unusually malleable: p53 binds zinc extremely tightly when folded, but is intrinsically unstable in the absenc...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2022-04-01
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| Edice: | Frontiers in Molecular Biosciences |
| Témata: | |
| On-line přístup: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.895887/full |
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