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Human immunodeficiency virus type 1 efficiently binds to human fetal astrocytes and induces neuroinflammatory responses independent of infection

<p>Abstract</p> <p>Background</p> <p>HIV-1 infects human astrocytes <it>in vitro </it>and <it>in vivo </it>but the frequency of infected cells is low and its biological significance is unknown. In studies <it>in vitro</it>, recombinant gp120 alone can induce profound effects on astrocyte biology, su...

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Principais autores: Potash Mary, Bentsman Galina, Li Jinliang, Volsky David J
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2007-05-01
Series:BMC Neuroscience
Acceso en liña:http://www.biomedcentral.com/1471-2202/8/31
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