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Activation of NF-κB by R5 and X4 Human Immunodeficiency Virus Type 1 Induces Macrophage Inflammatory Protein 1α and Tumor Necrosis Factor Alpha in Macrophages

NF-κB is a transcriptional activator that often regulates inflammatory responses. We demonstrate that human immunodeficiency virus type 1 activates nuclear localization of NF-κB in macrophages in a manner dependent upon virus strain but independent of virus replication. Through the use of an inhibit...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Choe, Wonkyu, Volsky, David J., Potash, Mary Jane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11967342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.10.5274-5277.2002
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