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Activation of NF-κB by R5 and X4 Human Immunodeficiency Virus Type 1 Induces Macrophage Inflammatory Protein 1α and Tumor Necrosis Factor Alpha in Macrophages

NF-κB is a transcriptional activator that often regulates inflammatory responses. We demonstrate that human immunodeficiency virus type 1 activates nuclear localization of NF-κB in macrophages in a manner dependent upon virus strain but independent of virus replication. Through the use of an inhibit...

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Autori principali: Choe, Wonkyu, Volsky, David J., Potash, Mary Jane
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136147/
https://ncbi.nlm.nih.gov/pubmed/11967342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5274-5277.2002
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