Alternative Lengthening of Telomeres: A Prognostic Paradox in Cancer
Telomere maintenance enables unlimited cell proliferation by counteracting telomere erosion. While the majority of tumors activate telomerase, a significant subset—approximately 10–15%—utilizes alternative lengthening of telomeres (ALT), a recombination-based mechanism. ALT-positive cancers are clas...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2025-10-01
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| Schriftenreihe: | Cells |
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| Online-Zugang: | https://www.mdpi.com/2073-4409/14/20/1613 |
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