Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to contribute to its pathogenesis. In the present stud...

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Principais autores:	Jana Meiners, Vittoria Palmieri, Robert Klopfleisch, Jana-Fabienne Ebel, Lukasz Japtok, Fabian Schumacher, Ayan Mohamud Yusuf, Katrin A. Becker, Julia Zöller, Matthias Hose, Burkhard Kleuser, Dirk M. Hermann, Richard N. Kolesnick, Jan Buer, Wiebke Hansen, Astrid M. Westendorf
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2019-06-01
Serija:	Frontiers in Immunology
Teme:	Citrobacter rodentium colitis acid sphingomyelinase amitriptyline Th1 Th17
Online dostop:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01386/full
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