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Astrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression

The ability of retroviruses (RVs) to cause neurodegeneration is critically dependent upon two activities of the envelope protein (Env). First, Env facilitates viral genome delivery to CNS target cells through receptor binding and membrane fusion. Second, Env expression within one or more targets ind...

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Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Sandra M. Cardona, Jaclyn M. Dunphy, Alvin S. Das, Connor R. Lynch, William P. Lynch
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2019-10-01
Rangatū:Frontiers in Neuroscience
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/article/10.3389/fnins.2019.01166/full
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