Functional Analysis of the env Open Reading Frame in Human Endogenous Retrovirus IDDMK(1,2)22 Encoding Superantigen Activity

Mice harbor a family of endogenous retroviruses, the mouse mammary tumor viruses (MMTV), which encode superantigens. These superantigens are responsible for the deletion of T cells expressing certain Vβ chains of the T-cell receptor in the thymus. Human T cells are able to recognize MMTV-encoded sup...

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Autors principals: Lapatschek, Matthias, Dürr, Susanne, Löwer, Roswitha, Magin, Christine, Wagner, Hermann, Miethke, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112145/
https://ncbi.nlm.nih.gov/pubmed/10864649
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