Repurposing MK-8245 as a Quorum Sensing Inhibitor to Suppress Virulence and Potentiate Antibiotic Activity in <i>Pseudomonas aeruginosa</i>

<b>Background/Objectives</b>: The rise in multidrug-resistant pathogens such as <i>Pseudomonas aeruginosa</i> (PA), coupled with declining antibiotic development, underscores the need for innovative therapeutic strategies. Repurposing approved drugs provides advantages of safety and rapid developmen...

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Prif Awduron:	Giulia Bernabè, Giovanni Marzaro, Mahmoud Elsayed Mosaad Shalata, Daniela Iosob, Valentina Inglima, Massimo Bellato, Ignazio Castagliuolo, Paola Brun
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2025-11-01
Cyfres:	Antibiotics
Pynciau:	biofilm antimicrobial resistance virulence quorum sensing inhibitors molecular docking
Mynediad Ar-lein:	https://www.mdpi.com/2079-6382/14/11/1116
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!