Repurposing MK-8245 as a Quorum Sensing Inhibitor to Suppress Virulence and Potentiate Antibiotic Activity in <i>Pseudomonas aeruginosa</i>

<b>Background/Objectives</b>: The rise in multidrug-resistant pathogens such as <i>Pseudomonas aeruginosa</i> (PA), coupled with declining antibiotic development, underscores the need for innovative therapeutic strategies. Repurposing approved drugs provides advantages of safety and rapid developmen...

Descripció completa

Dades bibliogràfiques

Autors principals:	Giulia Bernabè, Giovanni Marzaro, Mahmoud Elsayed Mosaad Shalata, Daniela Iosob, Valentina Inglima, Massimo Bellato, Ignazio Castagliuolo, Paola Brun
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-11-01
Col·lecció:	Antibiotics
Matèries:	biofilm antimicrobial resistance virulence quorum sensing inhibitors molecular docking
Accés en línia:	https://www.mdpi.com/2079-6382/14/11/1116
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!