Repurposing MK-8245 as a Quorum Sensing Inhibitor to Suppress Virulence and Potentiate Antibiotic Activity in <i>Pseudomonas aeruginosa</i>

<b>Background/Objectives</b>: The rise in multidrug-resistant pathogens such as <i>Pseudomonas aeruginosa</i> (PA), coupled with declining antibiotic development, underscores the need for innovative therapeutic strategies. Repurposing approved drugs provides advantages of safety and rapid developmen...

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Hlavní autoři:	Giulia Bernabè, Giovanni Marzaro, Mahmoud Elsayed Mosaad Shalata, Daniela Iosob, Valentina Inglima, Massimo Bellato, Ignazio Castagliuolo, Paola Brun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-11-01
Edice:	Antibiotics
Témata:	biofilm antimicrobial resistance virulence quorum sensing inhibitors molecular docking
On-line přístup:	https://www.mdpi.com/2079-6382/14/11/1116
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