Revisiting the antizyme 1 – ODC interaction reveals low-nanomolar affinity
Abstract Ornithine decarboxylase (ODC) catalyzes the rate-limiting step in polyamine biosynthesis and is one of the shortest-lived mammalian proteins. Its activity and proteasomal degradation are controlled by antizyme (AZ), which disrupts the active ODC homodimer and exposes proteasome-interacting...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer
2026-04-01
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| Reeks: | Amino Acids |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1007/s00726-026-03519-z |
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