Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target

Background Hypusination is an essential post-translational modification in eukaryotes. The two enzymes required for this modification, namely deoxyhypusine synthase (DHS) and deoxyhypusine hydrolase are also conserved. Plasmodium falciparum human malaria parasites possess genes for both hypusination...

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Главные авторы:	Aiyada Aroonsri, Navaporn Posayapisit, Jindaporn Kongsee, Onsiri Siripan, Danoo Vitsupakorn, Sugunya Utaida, Chairat Uthaipibull, Sumalee Kamchonwongpaisan, Philip J. Shaw
Формат:	Artigo
Язык:	Inglês
Опубликовано:	PeerJ Inc. 2019-04-01
Серии:	PeerJ
Предметы:	Hypusination glmS riboswitch PfDHS Deoxyhypusine synthase Plasmodium falciparum PfeIF5A
Online-ссылка:	https://peerj.com/articles/6713.pdf
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