Bio-nanocomplexes impair iron homeostasis to induce non-canonical ferroptosis in cancer cells

Abstract The targeted elevation of the labile iron pool (LIP) represents the most direct and effective strategy to induce ferroptosis in cancer cells. However, the efficiency of increasing LIP to induce ferroptosis via iron supplementation is controversial due to the iron homeostasis between LIP and...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Xin Wang, Tianyi Zhang, Shuai Wang, Hanping Shi, Hong Dong, Yanning Huang, Wenjia Lai, Yiqiao Hu, Chunyan Yue
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-02-01
Цуврал:	Journal of Nanobiotechnology
Нөхцлүүд:	Non-canonical ferroptosis Iron homeostasis HMOX1 Bio-nanocomplex CBS Labile iron pool
Онлайн хандалт:	https://doi.org/10.1186/s12951-025-03117-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!