Bio-nanocomplexes impair iron homeostasis to induce non-canonical ferroptosis in cancer cells

Abstract The targeted elevation of the labile iron pool (LIP) represents the most direct and effective strategy to induce ferroptosis in cancer cells. However, the efficiency of increasing LIP to induce ferroptosis via iron supplementation is controversial due to the iron homeostasis between LIP and...

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書誌詳細

主要な著者:	Xin Wang, Tianyi Zhang, Shuai Wang, Hanping Shi, Hong Dong, Yanning Huang, Wenjia Lai, Yiqiao Hu, Chunyan Yue
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-02-01
シリーズ:	Journal of Nanobiotechnology
主題:	Non-canonical ferroptosis Iron homeostasis HMOX1 Bio-nanocomplex CBS Labile iron pool
オンライン･アクセス:	https://doi.org/10.1186/s12951-025-03117-3
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