B12‐Cofactor Inactivation by Cobalt to Rhodium Mutation in Methylrhodibalamin: An Antivitamin B12 and Antibiotic

Cobalt‐corrins, such as coenzyme B12 (AdoCbl) and methylcobalamin (MeCbl), are indispensable enzyme‐cofactors found across all kingdoms of life. Their Rh‐homologues are promising coordination‐chemical and structural B12‐mimics. Herein, the preparation of methylrhodibalamin (MeRhbl) in over 90% yield...

詳細記述

書誌詳細

主要な著者:	Florian J. Widner, Klaus Wurst, Markus Ruetz, Christoph Kieninger, Christoph Kreutz, Michael D. Paxhia, Evelyne Deery, Martin J. Warren, Bernhard Kräutler
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley-VCH 2025-11-01
シリーズ:	ChemistryEurope
主題:	crystal structures enzyme inhibitors growth inhibitors organometallic catalysts vitamin B12
オンライン･アクセス:	https://doi.org/10.1002/ceur.202500157
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!