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Development and optimization of multivesicular gefitinib liposomal transdermal system employing lipoid S100 for breast cancer: pharmacokinetics, bioavailability, and skin irritation studies in Wistar rats

Abstract Background Conventional therapies in cancer treatment face challenges including drug resistance, lack of specificity, and severe adverse reactions. This study explores the potential of liposomal transdermal delivery systems as an alternative to current therapies with improved BA and PK. The...

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Autors principals: Jyoti S. Patel, Nulgumnalli Manjunathaiah Raghavendra, B. Sajeev Kumar
Format: Artigo
Idioma:Inglês
Publicat: SpringerOpen 2024-11-01
Col·lecció:Future Journal of Pharmaceutical Sciences
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Accés en línia:https://doi.org/10.1186/s43094-024-00729-8
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