Development and optimization of multivesicular gefitinib liposomal transdermal system employing lipoid S100 for breast cancer: pharmacokinetics, bioavailability, and skin irritation studies in Wistar rats

Abstract Background Conventional therapies in cancer treatment face challenges including drug resistance, lack of specificity, and severe adverse reactions. This study explores the potential of liposomal transdermal delivery systems as an alternative to current therapies with improved BA and PK. The...

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Автори:	Jyoti S. Patel, Nulgumnalli Manjunathaiah Raghavendra, B. Sajeev Kumar
Формат:	Artigo
Мова:	Inglês
Опубліковано:	SpringerOpen 2024-11-01
Серія:	Future Journal of Pharmaceutical Sciences
Предмети:	Central composite design Lipoid S100 Transdermal Gefitinib Liposomes Multivesicular vesicle
Онлайн доступ:	https://doi.org/10.1186/s43094-024-00729-8
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