The Effect of FTY720 on Sphingolipid Imbalance and Cognitive Decline in Aged EFAD Mice
Background: During Alzheimer’s disease (AD) progression, there is a decline in the bioactive sphingolipid sphingosine-1-phosphate (S1P). Previous research showed that FTY720, an S1P mimetic, prevented cognitive decline and reduced ceramide levels in transgenic mice with familial AD carrying the huma...
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| Główni autorzy: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
SAGE Publishing
2024-09-01
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| Seria: | Journal of Alzheimer's Disease Reports |
| Dostęp online: | https://doi.org/10.3233/ADR-230053 |
| Etykiety: |
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