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Translational Approaches Targeting Ceramide Generation From Sphingomyelin in T Cells to Modulate Immunity in Humans

In T cells, as in all other cells of the body, sphingolipids form important structural components of membranes. Due to metabolic modifications, sphingolipids additionally play an active part in the signaling of cell surface receptors of T cells like the T cell receptor or the co-stimulatory molecule...

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Bibliografische Detailangaben
Hauptverfasser: Claudia Hollmann, Teresa Wiese, Fabio Dennstädt, Julian Fink, Jürgen Schneider-Schaulies, Niklas Beyersdorf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-10-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2019.02363/full
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