SUMO1 Promotes Mesangial Cell Proliferation Through Inhibiting Autophagy in a Cell Model of IgA Nephropathy

IgA nephropathy (IgAN) is a common form of primary glomerulonephritis and its main pathological changes are mesangial cell proliferation and matrix expansion. Autophagy inhibition may result in its mesangial cell proliferation and renal lesions. SUMOylation is a eukaryotic-reversible post-translatio...

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Principais autores:	Xia Tan, Yexin Liu, Di Liu, Xiaofang Tang, Ming Xia, Guochun Chen, Liyu He, Xuejing Zhu, Hong Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-03-01
coleção:	Frontiers in Medicine
Assuntos:	SUMO1 autophagy IgA nephropathy mesangial cell proliferation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmed.2022.834164/full
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