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SUMO1 Promotes Mesangial Cell Proliferation Through Inhibiting Autophagy in a Cell Model of IgA Nephropathy

IgA nephropathy (IgAN) is a common form of primary glomerulonephritis and its main pathological changes are mesangial cell proliferation and matrix expansion. Autophagy inhibition may result in its mesangial cell proliferation and renal lesions. SUMOylation is a eukaryotic-reversible post-translatio...

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Principais autores: Xia Tan, Yexin Liu, Di Liu, Xiaofang Tang, Ming Xia, Guochun Chen, Liyu He, Xuejing Zhu, Hong Liu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-03-01
Serier:Frontiers in Medicine
Fag:
SUMO1
autophagy
IgA nephropathy
mesangial cell
proliferation
Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2022.834164/full
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