Medium from mesangial cells incubated with aggregated IgA1 from IgA nephropathy patients reduces podocyte adhesion through activation of the renin angiotensin system

BACKGROUND: Podocyte injury plays an important role in glomerulosclerosis in IgA nephropathy (IgAN), and detachment from the glomerular basement membrane is the main cause of podocyte damage. In a previous study we found that medium from mesangial cells incubated with aggregated IgA1 (aIgA1) i...

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Autores principales:	C Wang, X Liu, Y Tang, H Peng, ZC Ye, J Zhang, H Tang, T Lou
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	SMW supporting association (Trägerverein Swiss Medical Weekly SMW) 2011-12-01
Colección:	Swiss Medical Weekly
Materias:	adhesive IgA nephropathy IgA1 medium mesangial cell podocyte
Acceso en línea:	https://www.smw.ch/index.php/smw/article/view/1409
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