Role of Human Mesangial-Tubular Crosstalk in Secretory IgA-Induced IgA Nephropathy

Background: IgA nephropathy (IgAN) is characterized by the mesangial deposition of pathogenic IgA. We previously detected the deposition of pathogenic secretory IgA (SIgA) in the mesangium of about one-third of IgAN patients. Tubulointerstitial injury has an important role in the development of IgAN...

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Detalhes bibliográficos

Principais autores:	Junjun Zhang, Ruwen Zhou, Yiming Mi, Zhangsuo Liu, Bo Huang, Ruxue Guo, Panfei Wang, Songxia Quan, Yali Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Karger Publishers 2021-04-01
coleção:	Kidney & Blood Pressure Research
Assuntos:	iga nephropathy mucosal immunity secretory iga mesangial-tubular crosstalk
Acesso em linha:	https://www.karger.com/Article/FullText/514183
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