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In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line

Association of tau deposition with neurodegeneration in Alzheimer’s disease (AD) and related tau-positive neurological disorders collectively referred to as tauopathies indicates contribution of tau aggregates to neurotoxicity. The discovery of tau gene mutations in FTDP-17-tau kindreds has provided...

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Bibliografiske detaljer
Principais autores: Naruhiko Sahara, Masafumi Shimojo, Maiko Ono, Hiroyuki Takuwa, Marcelo Febo, Makoto Higuchi, Tetsuya Suhara
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-12-01
Serier:Frontiers in Neurology
Fag:
Online adgang:http://journal.frontiersin.org/article/10.3389/fneur.2017.00663/full
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