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Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

Alzheimer’s disease (AD) is characterized, amongst other features, by the pathologic accumulation of abnormally phosphorylated tau filaments in neurons that lead to neurofibrillary tangles. However, the molecular mechanisms by which the abnormal processing of tau leads to neurodegeneration and cogni...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Mireia Tondo, Brandi Wasek, Joan Carles Escola-Gil, David de Gonzalo-Calvo, Clinton Harmon, Erland Arning, Teodoro Bottiglieri
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: MDPI AG 2020-02-01
Цуврал:Metabolites
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/2218-1989/10/2/69
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