QR Code

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

Objective: Pro-peptide precursors are processed into biologically active peptide hormones or neurotransmitters, each playing an essential role in physiology and disease. Genetic loss of function of a pro-peptide precursor results in the simultaneous ablation of all biologically-active peptides withi...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Bhavani S. Sahu, Maria Razzoli, Seth McGonigle, Jean Pierre Pallais, Megin E. Nguyen, Masato Sadahiro, Cheng Jiang, Wei-Jye Lin, Kevin A. Kelley, Pedro Rodriguez, Rachel Mansk, Cheryl Cero, Giada Caviola, Paola Palanza, Loredana Rao, Megan Beetch, Emilyn Alejandro, Yuk Y. Sham, Andrea Frontini, Stephen R. Salton, Alessandro Bartolomucci
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2023-10-01
Rangatū:Molecular Metabolism
Ngā marau:
Pro-peptides
Mass spectrometry
Obesity
Point mutation
VGF
Granins
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2212877823001151
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Ngā tūemi rite