Activating and inhibitory Fcγ receptors in rheumatoid arthritis: from treatment to targeted therapies

Por van Roon, Joel AG
Publicado em 2007

Role of interleukin-7 in degenerative and inflammatory joint diseases

Por van Roon, Joel AG, Lafeber, Floris PJG
Publicado em 2008

Differentiation of naive CD4(+ )T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients

Por van Roon, Joël AG, Glaudemans, Catharina AFM, Bijlsma, Johannes WJ, Lafeber, Floris PJG
Publicado em 2003

Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation

Por Hartgring, Sarita AY, Willis, Cynthia R, Bijlsma, Johannes WJ, Lafeber, Floris PJG, van Roon, Joel AG
Publicado em 2012

Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis

Por Zweers, Manon C, de Boer, Tineke N, van Roon, Joël, Bijlsma, Johannes WJ, Lafeber, Floris PJG, Mastbergen, Simon C
Publicado em 2011

Synovial T cell hyporesponsiveness to myeloid dendritic cells is reversed by preventing PD-1/PD-L1 interactions

Por Moret, Frederique M, van der Wurff-Jacobs, Kim MG, Bijlsma, Johannes WJ, Lafeber, Floris PJG, van Roon, Joel AG
Publicado no Arthritis Res Ther (2014)

Decreased expression of TSLP in labial salivary glands of patients with primary Sjögren’s syndrome is associated with local- and systemic disease parameters

Por Hillen, Maarten R, Bikker, Angela, Kruize, Aike A, Wenting-van Wijk, Marion, Lafeber, Floris PJG, Hack, C Erik, Radstake, Timothy RDJ, van Roon, Joel AG
Publicado em 2012

Intra-articular CD1c-expressing myeloid dendritic cells from rheumatoid arthritis patients express a unique set of T cell-attracting chemokines and spontaneously induce Th1, Th17 a...

Por Moret, Frederique M, Hack, Cornelis E, van der Wurff-Jacobs, Kim MG, de Jager, Wilco, Radstake, Timothy RDJ, Lafeber, Floris PJG, van Roon, Joel AG
Publicado em 2013

Increased B-cell activating factor (BAFF)/B-lymphocyte stimulator (BLyS) in primary antiphospholipid syndrome is associated with higher adjusted global antiphospholipid syndrome sc...

Por van den Hoogen, Lucas L, Palla, Giovanni, Bekker, Cornelis P J, Fritsch-Stork, Ruth D E, Radstake, Timothy R D J, van Roon, Joel A G
Publicado no RMD Open (2018)

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade

Por Hillen, Maarten R., Hartgring, Sarita A. Y., Willis, Cynthia R., Radstake, Timothy R. D. J., Hack, Cornelis E., Lafeber, Floris P. J. G., van Roon, Joel A. G
Publicado no PLoS One (2015)

APL1, an altered peptide ligand derived from human heat-shock protein 60, increases the frequency of Tregs and its suppressive capacity against antigen responding effector CD4 + T...

Por Barberá, Ariana, Lorenzo, Noraylis, van Kooten, Peter, van Roon, Joel, de Jager, Wilco, Prada, Dinorah, Gómez, Jorge, Padrón, Gabriel, van Eden, Willem, Broere, Femke, del Carmen Domínguez, María
Publicado no Cell Stress Chaperones (2016)

Increased frequencies of circulating CXCL10-, CXCL8- and CCL4-producing monocytes and Siglec-3-expressing myeloid dendritic cells in systemic sclerosis patients

Por Carvalheiro, Tiago, Horta, Sara, van Roon, Joel A. G., Santiago, Mariana, Salvador, Maria J., Trindade, Hélder, Radstake, Timothy R. D. J., da Silva, José A. P., Paiva, Artur
Publicado no Inflamm Res (2017)

CXCL4 is a novel inducer of human Th17 cells and correlates with IL‐17 and IL‐22 in psoriatic arthritis

Por Affandi, Alsya J., Silva‐Cardoso, Sandra C., Garcia, Samuel, Leijten, Emmerik F. A., van Kempen, Tessa S., Marut, Wioleta, van Roon, Joel A. G., Radstake, Timothy R. D. J.
Publicado no Eur J Immunol (2018)

Persistence of interleukin 7 activity and levels on tumour necrosis factor α blockade in patients with rheumatoid arthritis

Por van Roon, Joel A G, Hartgring, Sarita A Y, Wijk, Marion Wenting‐van, Jacobs, Kim M G, Tak, Paul‐Peter, Bijlsma, Johannes W J, Lafeber, Floris P J G
Publicado em 2007

Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren’s syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?

Por Blokland, Sofie L M, Hillen, Maarten R, Wichers, Catharina G K, Zimmermann, Maili, Kruize, Aike A, Radstake, Timothy R D J, Broen, Jasper C A, van Roon, Joel A G
Publicado no RMD Open (2019)

Circulating small non-coding RNAs reflect IFN status and B cell hyperactivity in patients with primary Sjögren’s syndrome

Por Lopes, Ana P., Hillen, Maarten R., Chouri, Eleni, Blokland, Sofie L. M., Bekker, Cornelis P. J., Kruize, Aike A., Rossato, Marzia, van Roon, Joel A. G., Radstake, Timothy R. D. J.
Publicado no PLoS One (2018)

Interleukin-7 and Toll-Like Receptor 7 Induce Synergistic B Cell and T Cell Activation

Por Bikker, Angela, Kruize, Aike A., van der Wurff-Jacobs, Kim M. G., Peters, Rogier P., Kleinjan, Marije, Redegeld, Frank, de Jager, Wilco, Lafeber, Floris P. J. G., van Roon, Joël A. G.
Publicado em 2014

Salivary gland secretome: a novel tool towards molecular stratification of patients with primary Sjögren’s syndrome and non-autoimmune sicca

Por Blokland, Sofie L M, Hillen, Maarten R, van Vliet-Moret, Fréderique M, Bikker, Angela, de Jager, Wilco, Pandit, Aridaman, Kruize, Aike A, Radstake, Timothy R D J, van Roon, Joel A G
Publicado no RMD Open (2019)

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

Por Eijkelkamp, Niels, Steen-Louws, Cristine, Hartgring, Sarita A. Y., Willemen, Hanneke L. D. M., Prado, Judith, Lafeber, Floris P. J. G., Heijnen, Cobi J., Hack, C. E., van Roon, Joel A. G., Kavelaars, Annemieke
Publicado no J Neurosci (2016)

Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study

Por Bakker, Marije F, Cavet, Guy, Jacobs, Johannes WG, Bijlsma, Johannes W J, Haney, Douglas J, Shen, Yijing, Hesterberg, Lyndal K, Smith, Dustin R, Centola, Michael, van Roon, Joel A G, Lafeber, Floris P J G, Welsing, Paco M J
Publicado em 2012