Synovial T cell hyporesponsiveness to myeloid dendritic cells is reversed by preventing PD-1/PD-L1 interactions

INTRODUCTION: The aim of this study was to investigate PD-1/PD-L1 involvement in the hyporesponsiveness of rheumatoid arthritis (RA) synovial fluid (SF) CD4 T cells upon stimulation by thymic stromal lymphopoietin (TSLP)–primed CD1c myeloid dendritic cells (mDCs). METHODS: Expression of PD-1 on naïv...

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Detaylı Bibliyografya
Yayımlandı:Arthritis Res Ther
Asıl Yazarlar: Moret, Frederique M, van der Wurff-Jacobs, Kim MG, Bijlsma, Johannes WJ, Lafeber, Floris PJG, van Roon, Joel AG
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266919/
https://ncbi.nlm.nih.gov/pubmed/25433812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0497-x
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