CXCL4 is a novel inducer of human Th17 cells and correlates with IL‐17 and IL‐22 in psoriatic arthritis

CXCL4 regulates multiple facets of the immune response and is highly upregulated in various Th17‐associated rheumatic diseases. However, whether CXCL4 plays a direct role in the induction of IL‐17 production by human CD4(+) T cells is currently unclear. Here, we demonstrated that CXCL4 induced human...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Affandi, Alsya J., Silva‐Cardoso, Sandra C., Garcia, Samuel, Leijten, Emmerik F. A., van Kempen, Tessa S., Marut, Wioleta, van Roon, Joel A. G., Radstake, Timothy R. D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Immunodeficiencies and autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888178/
https://ncbi.nlm.nih.gov/pubmed/29193036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747195
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