Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist

Por Bonger, Kimberly M., Hoogendoorn, Sascha, van Koppen, Chris J., Timmers, C. Marco, van der Marel, Gijsbert A., Overkleeft, Herman S.
Publicado em 2010

Rescue of expression and signaling of human luteinizing hormone G protein-coupled receptor mutants with an allosterically binding small-molecule agonist

Por Newton, Claire L., Whay, Adele M., McArdle, Craig A., Zhang, Meilin, van Koppen, Chris J., van de Lagemaat, Ruud, Segaloff, Deborah L., Millar, Robert P.
Publicado em 2011

Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor

Por van Koppen, Chris J, de Gooyer, Marcel E, Karstens, Willem-Jan, Plate, Ralf, Conti, Paolo GM, van Achterberg, Tanja AE, van Amstel, Monique GA, Brands, Jolanda HGM, Wat, Jesse, Berg, Rob JW, Lane, J Robert D, Miltenburg, Andre MM, Timmers, C Marco
Publicado em 2012

Discovery of Triazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys

Por Hoyt, Scott B., Petrilli, Whitney, London, Clare, Liang, Gui-Bai, Tata, Jim, Hu, Qingzhong, Yin, Lina, van Koppen, Chris J., Hartmann, Rolf W., Struthers, Mary, Wisniewski, Tom, Ren, Ning, Bopp, Charlene, Sok, Andrea, Cai, Tian-Quan, Stribling, Sloan, Pai, Lee-Yuh, Ma, Xiuying, Metzger, Joe, Verras, Andreas, McMasters, Daniel, Chen, Qing, Tung, Elaine, Tang, Wei, Salituro, Gino, Buist, Nicole, Clemas, Joe, Zhou, Gaochao, Gibson, Jack, Maxwell, Carrie Ann, Lassman, Mike, McLaughlin, Theresa, Castro-Perez, Jose, Szeto, Daphne, Forrest, Gail, Hajdu, Richard, Rosenbach, Mark, Xiong, Yusheng
Publicado no ACS Med Chem Lett (2015)