Immunomodulatory and Kidney-Protective Effects of the Human Chorionic Gonadotropin Derivate EA-230

od van Groenendael, Roger, Kox, Matthijs, van Eijk, Lucas T., Pickkers, Peter
Wydane w Nephron Clin Pract (2018)

Pharmacokinetics, safety and tolerability of the novel β‐hCG derived immunomodulatory compound, EA‐230

od van Groenendael, Roger, Aarnoutse, Rob, Kox, Matthijs, van Eijk, Lucas, Pickkers, Peter
Wydane w Br J Clin Pharmacol (2019)

A randomized double‐blind, placebo‐controlled clinical phase IIa trial on safety, immunomodulatory effects and pharmacokinetics of EA‐230 during experimental human endotoxaemia...

od van Groenendael, Roger, Kox, Matthijs, Leijte, Guus, Koeneman, Bouke, Gerretsen, Jelle, van Eijk, Lucas, Pickkers, Peter
Wydane w Br J Clin Pharmacol (2019)

The Safety, Tolerability, and Effects on the Systemic Inflammatory Response and Renal Function of the Human Chorionic Gonadotropin Hormone-Derivative EA-230 Following On-Pump Cardi...

od van Groenendael, Roger, Beunders, Remi, Hofland, Jan, Morshuis, Wim J, Kox, Matthijs, van Eijk, Lucas T, Pickkers, Peter
Wydane w JMIR Res Protoc (2019)

Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia

od Kiers, Dorien, van Eijk, Lucas T., van der Hoeven, Johannes G., Swinkels, Dorine W., Pickkers, Peter, Kox, Matthijs
Wydane w Haematologica (2019)

Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study

od van Eijk, Lucas T, Kroot, Joyce JC, Tromp, Mirjam, van der Hoeven, Johannes G, Swinkels, Dorine W, Pickkers, Peter
Wydane 2011

Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in Humans in vivo

od Beunders, Remi, Schütz, Maren J., van Groenendael, Roger, Leijte, Guus P., Kox, Matthijs, van Eijk, Lucas T., Pickkers, Peter
Wydane w Front Med (Lausanne) (2020)

Microvascular permeability during experimental human endotoxemia: an open intervention study

od van Eijk, Lucas TGJ, Pickkers, Peter, Smits, Paul, Broek, Wim van den, Bouw, Martijn PWJM, van der Hoeven, Johannes G
Wydane 2005

Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane

od Dinkla, Sip, van Eijk, Lucas T., Fuchs, Beate, Schiller, Jürgen, Joosten, Irma, Brock, Roland, Pickkers, Peter, Bosman, Giel J.C.G.M.
Wydane w BBA Clin (2016)

Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

od Kox, Matthijs, van Eijk, Lucas T., Zwaag, Jelle, van den Wildenberg, Joanne, Sweep, Fred C. G. J., van der Hoeven, Johannes G., Pickkers, Peter
Wydane 2014

Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study

od Kox, Matthijs, van Eijk, Lucas T., Verhaak, Tim, Frenzel, Tim, Kiers, Harmke D., Gerretsen, Jelle, van der Hoeven, Johannes G., Kornet, Lilian, Scheiner, Avram, Pickkers, Peter
Wydane w Arthritis Res Ther (2015)

Systemic Inflammation Decreases Pain Threshold in Humans In Vivo

od de Goeij, Moniek, van Eijk, Lucas T., Vanelderen, Pascal, Wilder-Smith, Oliver H., Vissers, Kris C., van der Hoeven, Johannes G., Kox, Matthijs, Scheffer, Gert Jan, Pickkers, Peter
Wydane 2013

The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys

od Schwoebel, Frank, van Eijk, Lucas T., Zboralski, Dirk, Sell, Simone, Buchner, Klaus, Maasch, Christian, Purschke, Werner G., Humphrey, Martin, Zöllner, Stefan, Eulberg, Dirk, Morich, Frank, Pickkers, Peter, Klussmann, Sven
Wydane 2013

The effect of iron loading and iron chelation on the innate immune response and subclinical organ injury during human endotoxemia: a randomized trial

od van Eijk, Lucas T., Heemskerk, Suzanne, van der Pluijm, Rob W., van Wijk, Susanne M., Peters, Wilbert H.M., van der Hoeven, Johannes G., Kox, Matthijs, Swinkels, Dorine W, Pickkers, Peter
Wydane 2014

Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans

od van Eijk, Lucas T., John, Aaron S. E., Schwoebel, Frank, Summo, Luciana, Vauléon, Stéphanie, Zöllner, Stefan, Laarakkers, Coby M., Kox, Matthijs, van der Hoeven, Johannes G., Swinkels, Dorine W., Riecke, Kai, Pickkers, Peter
Wydane 2014

Safety and Efficacy of Human Chorionic Gonadotropin Hormone-Derivative EA-230 in Cardiac Surgery Patients: A Randomized Double-Blind Placebo-Controlled Study

od van Groenendael, Roger, Beunders, Remi, Hemelaar, Pleun, Hofland, Jan, Morshuis, Wim J., van der Hoeven, Johannes G., Gerretsen, Jelle, Wensvoort, Gert, Kooistra, Emma J., Claassen, Wout J., Waanders, Denise, Lamberts, Maud G. A., Buijsse, Leonie S. E., Kox, Matthijs, van Eijk, Lucas T., Pickkers, Peter
Wydane w Crit Care Med (2021)

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation

od Kiers, Dorien, Wielockx, Ben, Peters, Esther, van Eijk, Lucas T., Gerretsen, Jelle, John, Aaron, Janssen, Emmy, Groeneveld, Rianne, Peters, Mara, Damen, Lars, Meneses, Ana M., Krüger, Anja, Langereis, Jeroen D., Zomer, Aldert L., Blackburn, Michael R., Joosten, Leo A., Netea, Mihai G., Riksen, Niels P., van der Hoeven, Johannes G., Scheffer, Gert-Jan, Eltzschig, Holger K., Pickkers, Peter, Kox, Matthijs
Wydane w EBioMedicine (2018)