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The effect of iron loading and iron chelation on the innate immune response and subclinical organ injury during human endotoxemia: a randomized trial

In this double-blind randomized placebo-controlled trial involving 30 healthy male volunteers we investigated the acute effects of iron loading (single dose of 1.25 mg/kg iron sucrose) and iron chelation therapy (single dose of 30 mg/kg deferasirox) on iron parameters, oxidative stress, the innate i...

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Detalhes bibliográficos
Main Authors: van Eijk, Lucas T., Heemskerk, Suzanne, van der Pluijm, Rob W., van Wijk, Susanne M., Peters, Wilbert H.M., van der Hoeven, Johannes G., Kox, Matthijs, Swinkels, Dorine W, Pickkers, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943324/
https://ncbi.nlm.nih.gov/pubmed/24241495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.088047
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