Identification of New Human Malaria Parasite Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening

Por Pavadai, Elumalai, El Mazouni, Farah, Wittlin, Sergio, de Kock, Carmen, Phillips, Margaret A., Chibale, Kelly
Publicado no J Chem Inf Model (2016)

Ruthenium(II) arene complexes with chelating chloroquine analogue ligands: Synthesis, characterization and in vitro antimalarial activity

Por Glans, Lotta, Ehnbom, Andreas, de Kock, Carmen, Martínez, Alberto, Estrada, Jesús, Smith, Peter J., Haukka, Matti, Sánchez-Delgado, Roberto A., Nordlander, Ebbe
Publicado em 2012

Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice

Por Melariri, Paula, Kalombo, Lonji, Nkuna, Patric, Dube, Admire, Hayeshi, Rose, Ogutu, Benhards, Gibhard, Liezl, deKock, Carmen, Smith, Peter, Wiesner, Lubbe, Swai, Hulda
Publicado no Int J Nanomedicine (2015)

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Por Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Cabrera, Diego Gonzàlez, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn-Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly
Publicado no Antimicrob Agents Chemother (2018)

Erratum for Brunschwig et al., “UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria”

Por Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Gonzàlez Cabrera, Diego, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn-Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly
Publicado no Antimicrob Agents Chemother (2018)