Artesunate Activation by Heme in an Aqueous Medium

door Heller, Laura, Roepe, Paul D., de Dios, Angel C.
Gepubliceerd in Inorganica Chim Acta (2019)

Relative to Quinine and Quinidine, Their 9-Epimers Exhibit Decreased Cytostatic Activity and Altered Heme Binding but Similar Cytocidal Activity versus Plasmodium falciparum

door Gorka, Alexander P., Sherlach, Katy S., de Dios, Angel C., Roepe, Paul D.
Gepubliceerd in 2013

The Hydroxyl Functionality and a Rigid Proximal N are Required for Forming a Novel Non-Covalent Quinine-Heme Complex

door Alumasa, John N., Gorka, Alexander P., Casabianca, Leah B., Comstock, Erica, de Dios, Angel C., Roepe, Paul D.
Gepubliceerd in 2010

Quinine and Chloroquine Differentially Perturb Heme Monomer–Dimer Equilibrium

door Casabianca, Leah B., An, David, Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Gepubliceerd in 2008

Overcoming Drug Resistance to Heme-Targeted Antimalarials by Systematic Side Chain Variation of 7-Chloro-4-aminoquinolines

door Yearick, Kim, Ekoue-Kovi, Kekeli, Iwaniuk, D., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Gepubliceerd in 2008

Antimalarial Drugs and Heme in Detergent Micelles: An NMR Study

door Casabianca, Leah B., Kallgren, Joye B., Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Gepubliceerd in 2009

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

door Ekoue-Kovi, Kekeli, Yearick, Kimberly, Iwaniuk, Daniel P., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Gepubliceerd in 2008

Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain

door Iwaniuk, Daniel P., Whetmore, Eric D., Rosa, Nicholas, Ekoue-Kovi, Kekeli, Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Gepubliceerd in 2009

4-N, 4-S & 4-O Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen pKa on Activity vs. Chloroquine Resistant Malaria,

door Natarajan, Jayakumar K., Alumasa, John, Yearick, Kimberly, Ekoue-Kovi, Kekeli A., Casabianca, Leah B., de Dios, Angel C., Wolf, Christian, Roepe, Paul D.
Gepubliceerd in 2008

Cytostatic versus Cytocidal Activities of Chloroquine Analogues and Inhibition of Hemozoin Crystal Growth

door Gorka, Alexander P., Alumasa, John N., Sherlach, Katy S., Jacobs, Lauren M., Nickley, Katherine B., Brower, Jonathan P., de Dios, Angel C., Roepe, Paul D.
Gepubliceerd in 2013