Artesunate Activation by Heme in an Aqueous Medium

par Heller, Laura, Roepe, Paul D., de Dios, Angel C.
Publié dans Inorganica Chim Acta (2019)

Relative to Quinine and Quinidine, Their 9-Epimers Exhibit Decreased Cytostatic Activity and Altered Heme Binding but Similar Cytocidal Activity versus Plasmodium falciparum

par Gorka, Alexander P., Sherlach, Katy S., de Dios, Angel C., Roepe, Paul D.
Publié 2013

The Hydroxyl Functionality and a Rigid Proximal N are Required for Forming a Novel Non-Covalent Quinine-Heme Complex

par Alumasa, John N., Gorka, Alexander P., Casabianca, Leah B., Comstock, Erica, de Dios, Angel C., Roepe, Paul D.
Publié 2010

Quinine and Chloroquine Differentially Perturb Heme Monomer–Dimer Equilibrium

par Casabianca, Leah B., An, David, Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Publié 2008

Overcoming Drug Resistance to Heme-Targeted Antimalarials by Systematic Side Chain Variation of 7-Chloro-4-aminoquinolines

par Yearick, Kim, Ekoue-Kovi, Kekeli, Iwaniuk, D., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publié 2008

Antimalarial Drugs and Heme in Detergent Micelles: An NMR Study

par Casabianca, Leah B., Kallgren, Joye B., Natarajan, Jayakumar K., Alumasa, John N., Roepe, Paul D., Wolf, Christian, de Dios, Angel C.
Publié 2009

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

par Ekoue-Kovi, Kekeli, Yearick, Kimberly, Iwaniuk, Daniel P., Natarajan, Jayakumar K., Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publié 2008

Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain

par Iwaniuk, Daniel P., Whetmore, Eric D., Rosa, Nicholas, Ekoue-Kovi, Kekeli, Alumasa, John, de Dios, Angel C., Roepe, Paul D., Wolf, Christian
Publié 2009

4-N, 4-S & 4-O Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen pKa on Activity vs. Chloroquine Resistant Malaria,

par Natarajan, Jayakumar K., Alumasa, John, Yearick, Kimberly, Ekoue-Kovi, Kekeli A., Casabianca, Leah B., de Dios, Angel C., Wolf, Christian, Roepe, Paul D.
Publié 2008

Cytostatic versus Cytocidal Activities of Chloroquine Analogues and Inhibition of Hemozoin Crystal Growth

par Gorka, Alexander P., Alumasa, John N., Sherlach, Katy S., Jacobs, Lauren M., Nickley, Katherine B., Brower, Jonathan P., de Dios, Angel C., Roepe, Paul D.
Publié 2013